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effects with Examination of human urine samples indicates that human UGT1A3 and UGT2B7 would be the predominant isoforms to blame for generating the key urinary metabolites of JWH-018 and JWH-073 (Chimalakonda et al., 2011b). It is important to focus on that While these isoforms are present in large stages while in the liver, Also they are expresse